Advances in Chronic Lymphocytic Leukemia

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Malek, Sami (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2013.
• Σειρά: Advances in Experimental Medicine and Biology, 792
• Θέματα: Medicine.; Cancer research.; Biomedicine.; Cancer Research.

Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. CLL has a highly varied clinical course.  While advances in CLL therapy are noted, many patients still succumb to this illness. Like most progress in medicine, solid advances in the diagnosis, prognosis and treatmen...

Πίνακας περιεχομένων:

• Preface
• B-cell receptor and antigens in CLL
• The CLL cell microenvironment
• Acquired genomic copy number aberrations in CLL
• Recurrent gene mutations in CLL
• TP53 aberrations in CLL
• Gene expression and epigenetic deregulation
• Apoptosis deregulation in CLL
• Richter’s Syndrome
• Molecular biomarkers in chronic lymphocytic leukemia
• Critical Signal Transduction Pathways in CLL
• Immunotherapies in CLL
• Novel therapeutic agents in CLL
• Inherited susceptibility to CLL
• miR deregulations in CLL
• Index.