Epigenetics and Complex Traits

Epigenetics and Complex Traits provides an overview of basic epigenetic phenomena that influence transmission of genetic traits, including the pivotal roles of epigenetic factors in genome integrity, genetic transmission and phenotypic variation at critical developmental points, interactions between...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Naumova, Anna K. (Επιμελητής έκδοσης), Greenwood, Celia M.T (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2013.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Part I: Epigenetic phenomena in the germ line and early embryonic development and their effects on the inheritance of genetic traits
  • Epigenetic reprogramming in the mammalian germ line
  • Establishment of tissue-specific epigenetic states during development
  • X-chromosome Inactivation
  • Cis- and trans-effects underlying polar overdominance at the callipyge locus
  • Transgenerational epigenetic effects and complex inheritance patterns
  • Autosomal monoallelic expression
  • Part II: Epigenetic variation in health and disease
  • Recurrent CNVs in the etiology of epigenetic neurodevelopmental disorders
  • Impact of the early-life environment on the epigenome and behavioral development
  • Interaction between genetics and epigenetics in cancer
  • Part III: Impact of epigenetics on complex trait genetics and analysis
  • Epigenetic variation, phenotypic heritability, and evolution
  • Statistical Approaches for Detecting Transgenerational Genetic Effects in Humans
  • Transmission ratio distortion: a neglected phenomenon with many consequences in genetic analysis and population genetics
  • Epigenome Wide Association Studies: Potential insights into human disease
  • Analytical Considerations for Epigenome-wide Association Scans of Complex Traits
  • Index.                             .