Non-coding RNAs and Cancer

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Fabbri, Muller (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2014.
• Θέματα: Medicine.; Cancer research.; Human genetics.; Gene expression.; Biochemistry.; Posttranslational modification.; Cell biology.; Biomedicine.; Cancer Research.; Cell Biology.; Biochemistry, general.; Posttranslational Modification.; Gene Expression.; Human Genetics.

The discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and its implications in cancer are emerging as well, suggesting a b...

Πίνακας περιεχομένων:

• Introduction
• Biogenesis and Physiology of microRNAs.-Detecting non-coding RNA expression: from arrays to next generation sequencing
• MicroRNAs in Solid Tumors.-MicroRNAs in hematologic malignancies
• miRNAs as Cancer Biomarkers
• Unraveling the complex network of interactions between non-coding RNAs and epigenetics in cancer
• MicroRNA SNPs in Cancer
• Bioinformatics Approaches to the study of microRNAs
• Beyond miRNAs: role of other non-coding RNAs in cancer
• Translational Implications for non-coding RNA in Cancer
• Index.