Fundamentals of Chromatin

• Corporate Author: SpringerLink (Online service)
• Other Authors: Workman, Jerry L. (Editor), Abmayr, Susan M. (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2014.
• Subjects: Medicine.; Human genetics.; Gene expression.; Biomedicine.; Human Genetics.; Biomedicine general.; Gene Expression.

Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. It is essential for packaging DNA, regulation of gene expression, DNA replication and repair. The audience for this book includes newly established scientists, graduate students and scientists seeking...

Table of Contents:

• Preface
• Histone, Nucleosome and Chromatin Structure
• Histone Chaperones in the Assembly and Disassembly of Chromatin
• Chromatin Remodeling Complexes
• Regulating Chromatin by Histone Acetylation
• Histone Methylation in Chromatin Signaling
• Histone Ubiquitylation Control of Gene Expression
• Regulation of Chromatin Structure and Function by PARP-1 and ADP-ribosylation
• Histone phosphorylation and chromatin dynamics
• Reading histone modifications
• Properties and functions of histone variants
• Transcription through Chromatin
• Chromatin remodeling in DNA repair and replication
• Heterochromatin: A Critical Part of the Genome
• Emerging Areas of Chromatin Research
• Index.