Systems Analysis of Human Multigene Disorders

• Corporate Author: SpringerLink (Online service)
• Other Authors: Maltsev, Natalia (Editor), Rzhetsky, Andrey (Editor), Gilliam, T. Conrad (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2014.
• Series: Advances in Experimental Medicine and Biology, 799
• Subjects: Life sciences.; Human genetics.; Systems biology.; Life Sciences.; Systems Biology.; Human Genetics.

Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with sys...

Table of Contents:

• Wellness and Health Omics Linked to the Environment: the WHOLE approach to personalized medicine
• Characterizing Multi-omic Data in Systems Biology
• High-throughput Translational Medicine: Challenges and Solutions
• Computational approaches for human disease gene prediction and ranking
• A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization
• Index.