Cell Death Mechanism and Disease /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Wu, Hao (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2014.
• Θέματα: Life sciences.; Proteins.; Cell biology.; Cell physiology.; Apoptosis.; Life Sciences.; Cell Biology.; Cell Physiology.; Receptors.; Biomedicine general.

Beginning from centuries of anecdotal descriptions of cell death, such as those on the development of the midwife toad in 1842 by Carl Vogt, to modern-day investigations of cell death as a biological discipline, it has become accepted that cell death in multicellular organisms is a normal part of li...

Πίνακας περιεχομένων:

• 1. Historical Perspective – the Seven Ages of Cell Death Research
• 2. The Intrinsic Apoptotic Pathway
• 3. Molecular Basis of Cell Death Programs in Mature T Cell Homeostasis
• 4. Bcl-2 family and their therapeutic potential
• 5. IAP proteins and their therapeutic potential
• 6. Cell Death and Cancer
• 7. The DNA damage response mediates apoptosis and tumor suppression
• 8. Neuronal Death Mechanisms in Development and Disease
• 9. The Complex Interplay Between Metabolism and Apoptosis
• 10. Programmed Necrosis/Necroptosis: An Inflammatory Form of Cell Death
• 11. Structural Perspectives on BCL-2 Family of Proteins
• 12. Structural basis of death receptor signaling.