Diabetic Cardiomyopathy Biochemical and Molecular Mechanisms /
Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus a...
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| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
New York, NY :
Springer New York : Imprint: Springer,
2014.
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| Series: | Advances in Biochemistry in Health and Disease ;
9 |
| Subjects: | |
| Online Access: | Full Text via HEAL-Link |
Table of Contents:
- Cardiac defects in diabetes
- Hormonal imbalance and neuropathy
- Role of oxidative stress
- Role of cation channel defects
- Abnormalities in glucose transport
- Fatty acid utilization
- Sarcolemmal Na+-K+ ATPase
- Sarcolemmal Ca2+-transport
- Sarcoplasmic reticular Ca2+-transport
- Intracellular Ca2+-homeostasis
- Mitochondrial function
- Contractile proteins
- β-adrenoceptor mechanisms
- Protein kinases and signal transduction
- Regulation of phopholipases
- Endothelin defects and cardiac dysfunction
- Metabolic changes in smooth muscles
- Metabolic defects in skeletal muscles
- Metabolic defects in brain
- Role of microangiopathy in heart dysfunction
- Role of nephropathy in heart dysfunction
- Prevention of diabetic-induced cardiac dysfunction
- Molecular targets for the therapy of diabetic cardiomyopathy.
