MicroRNA in Development and in the Progression of Cancer

MicroRNAs (miRNAs) are small 22-nucleotides long non-coding RNAs that regulate the gene expression through translational repression and mRNA degradation in varieties of species. miRNAs play regulatory role in several fundamental biological processes from normal development to regulation of stem cell...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Singh, Shree Ram (Επιμελητής έκδοσης), Rameshwar, Pranela (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2014.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
LEADER 03673nam a22004815i 4500
001 978-1-4899-8065-6
003 DE-He213
005 20151204163215.0
007 cr nn 008mamaa
008 140421s2014 xxu| s |||| 0|eng d
020 |a 9781489980656  |9 978-1-4899-8065-6 
024 7 |a 10.1007/978-1-4899-8065-6  |2 doi 
040 |d GrThAP 
050 4 |a RC261-271 
072 7 |a MJCL  |2 bicssc 
072 7 |a MED062000  |2 bisacsh 
082 0 4 |a 614.5999  |2 23 
245 1 0 |a MicroRNA in Development and in the Progression of Cancer  |h [electronic resource] /  |c edited by Shree Ram Singh, Pranela Rameshwar. 
264 1 |a New York, NY :  |b Springer New York :  |b Imprint: Springer,  |c 2014. 
300 |a XIII, 407 p. 47 illus., 38 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 |a Preface -- miRNA biogenesis and function -- miRNAs in cancer progression -- MicroRNA, DNA repair and cancer -- Role of microRNAs in stem cells regulation and tumorigenesis in Drosophila -- MicroRNAs in stem cells and cancer stem cells -- MicroRNAs in epithelial mesenchymal transition and breast cancer progression -- MicroRNAs in the development and progression of breast cancer -- The role of microRNAs in hematopoietic stem cells and leukemia development -- MiRNA and chronic lymphocytic leukemia -- The role of miRNAs in the development of normal pancreas and pancreatic cancer, and their roles in tumor progression -- Epigenetic regulation of microRNA genes in colorectal cancer -- MicroRNAs in the development and progression of kidney cancer -- MicroRNAs in the development and progression of skin cancer -- MicroRNAs in the Development and Progression of Prostate Cancer -- MicroRNAs in development and progression of ovarian cancer -- MicroRNA and Cancer Drug Resistance -- Microvesicular Transfer of microRNA in Tumor Microenvironment -- MicroRNA cancer therapeutics and the challenge of drug delivery -- MicroRNA and Drug Delivery -- Index. 
520 |a MicroRNAs (miRNAs) are small 22-nucleotides long non-coding RNAs that regulate the gene expression through translational repression and mRNA degradation in varieties of species. miRNAs play regulatory role in several fundamental biological processes from normal development to regulation of stem cells, cancer stem cells and various human diseases including cancer. miRNAs can be used as potential biomarkers for disease diagnosis and have been considered potential therapeutic strategies in cancer treatment. This is a timely and specialized book providing the current understanding of miRNAs and their potential application in cancer diagnosis, prognosis, and therapeutic strategies in cancer treatment. This book will be a valuable source of information for the scientists in the field of cancer research as well as undergraduate and graduate students who want to pursue their research careers in cancer biology. 
650 0 |a Medicine. 
650 0 |a Cancer research. 
650 0 |a Gene expression. 
650 0 |a Medical microbiology. 
650 1 4 |a Biomedicine. 
650 2 4 |a Cancer Research. 
650 2 4 |a Gene Expression. 
650 2 4 |a Medical Microbiology. 
650 2 4 |a Biomedicine general. 
700 1 |a Singh, Shree Ram.  |e editor. 
700 1 |a Rameshwar, Pranela.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9781489980649 
856 4 0 |u http://dx.doi.org/10.1007/978-1-4899-8065-6  |z Full Text via HEAL-Link 
912 |a ZDB-2-SBL 
950 |a Biomedical and Life Sciences (Springer-11642)