Correlation-based network analysis of cancer metabolism A new systems biology approach in metabolomics /

• Main Authors: Armitage, Emily G. (Author), Kotze, Helen L. (Author), Williams, Kaye J. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2014.
• Series: SpringerBriefs in Systems Biology,
• Subjects: Life sciences.; Cancer research.; Systems biology.; Metabolism.; Life Sciences.; Systems Biology.; Metabolomics.; Cancer Research.

With the rise of systems biology as an approach in biochemistry research, using high throughput techniques such as mass spectrometry to generate metabolic profiles of cancer metabolism is becoming increasingly popular. There are examples of cancer metabolic profiling studies in the academic literatu...

Table of Contents:

• An overview of Cancer metabolism
• Cancer hypoxia and the tumour microenvironment as effectors of cancer metabolism
• Metabolic fingerprinting of in vitro cancer cell samples
• Network-based correlation analysis of metabolic fingerprinting data
• Case study: Systems biology of HIF metabolism in cancer
• Case study: Systems biology of chemotherapy resistance in hypoxic cancer
• Index.