Molecular mechanisms and physiology of disease Implications for Epigenetics and Health /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Maulik, Nilanjana (Επιμελητής έκδοσης), Karagiannis, Tom (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2014.
• Θέματα: Medicine.; Gene expression.; Human physiology.; Molecular biology.; Respiratory organs > Diseases.; Medical biochemistry.; Proteins.; Biomedicine.; Human Physiology.; Medical Biochemistry.; Molecular Medicine.; Protein Science.; Gene Expression.; Pneumology/Respiratory System.

In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes incl...

Πίνακας περιεχομένων:

• Epigenetics in Childhood Health and Disease
• Role of Epigenetics in Neural Differentiation: Implications for Health and Disease
• An Overview of Epigenetic Mechanisms in Health and Disease
• Epigenetics: Role of Histone Proteases in Cellular Functions and Diseases
• Anti-inflammatory Effects of Probiotics and their Metabolites – Possible Role for Epigenetic Effects
• Epigenetics of Autoimmune Diseases
• The Effect of Nutrition and Exercise on Epigenetics and the Development of Cardiovascular Disease
• Epigenetic Events Associated with Obesity and Diabetes
• Molecular Mechanisms in the Development and Progression of Asthma: The Role of Epigenetic Regulation and the Airway Epithelium
• The Significance of Nanoparticles in Medicine and their Potential in Asthma
• One-carbon Metabolism Nutrients and Epigenetics: A Mechanistic Link Between Aberrant One-carbon Metabolism and Cancer Risk?
• Principles of the Warburg Effect and Cancer Metabolism
• Molecular Aspects of the Warburg Effect
• Epigenetic Perturbations in the Context of the Multi-hit Hypothesis of Carcinogenesis
• Epigenetic Mechanisms of Colon Cancer Prevention
• Dietary Antioxidants and Chromatin Modifying Compounds as Potential Anticancer Therapies
• Combination Therapy for Cancer – Phototherapy and HDAC Inhibition
• Nano-base Drug Delivery Modalities for the Treatment of Cancer: The Formulation of Tumour-specific and –targeted Nanoparticles.