Next Generation Sequencing Technologies and Challenges in Sequence Assembly

• Main Authors: El-Metwally, Sara (Author), Ouda, Osama M. (Author), Helmy, Mohamed (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2014.
• Series: SpringerBriefs in Systems Biology, 7
• Subjects: Life sciences.; Human genetics.; Bioinformatics.; Systems biology.; Life Sciences.; Systems Biology.; Human Genetics.

The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own ch...

Table of Contents:

• Basics of Molecular Biology for Next-generation Sequencing
• Algorithms and Data Structures in Next-generation Sequencing
• First- and Next-generations Sequencing Models
• Next-generation Sequencing Platforms
• Challenges in Next-generation Sequencing Field
• New Horizons in Next-generation Sequencing
• Novel Next-generation Sequencing Applications
• Next-generation Sequence Assembly Overview
• Approaches and Challenges of Next-generation Sequence Assembly Stages
• Assessment of Next-generation Sequence Assembly
• Next-generation Sequence Assemblers
• Concluding Remarks.