Lasso Peptides Bacterial Strategies to Make and Maintain Bioactive Entangled Scaffolds /

• Main Authors: Li, Yanyan (Author), Zirah, Séverine (Author), Rebuffat, Sylvie (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2015.
• Series: SpringerBriefs in Microbiology,
• Subjects: Medicine.; Immunology.; Medical microbiology.; Vaccines.; Biomedicine.; Medical Microbiology.; Vaccine.

Lasso peptides form a growing family of fascinating ribosomally-synthesized and post-translationally modified peptides produced by bacteria. They contain 15 to 24 residues and share a unique interlocked topology that involves an N-terminal 7 to 9-residue macrolactam ring where the C-terminal tail is...

Table of Contents:

• Overview on Lasso Peptide Research
• From the Producer Microorganisms to the Lasso Scaffold
• Biological Activities of Lasso Peptides and Structure-Activity Relationships
• Biosynthesis, Regulation and Export of Lasso Peptides
• Lasso Peptide Bioengineering and Bioprospecting.