Cholesterol Transporters of the START Domain Protein Family in Health and Disease START Proteins - Structure and Function /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Clark, Barbara J. (Editor), Stocco, Douglas M. (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2014.
• Subjects: Medicine.; Endocrinology.; Proteins.; Medicine & Public Health.; Protein Science.; Biomedicine general.

Non-vesicular intracellular cholesterol transport is an important mechanism for maintaining membrane cholesterol homeostasis. Recent reports of studies directed at soluble cholesterol transport proteins indicate that aberrant expression of the START proteins may contribute to disease states associat...

Table of Contents:

• An Introduction to the Steroidogenic Acute Regulatory Protein (StAR)-related Lipid Transfer Domain Protein Family
• The Steroidogenic Acute Regulatory Protein (StAR)
• START domain protein structure and ligand specificity
• Congenital Lipoid Adrenal Hyperplasia
• Steroidogenic Acute Regulatory protein (StAR) and Atherogenesis
• STARD3: a lipid transfer protein in breast cancer and cholesterol trafficking
• The STARD4 subfamily: STARD4 and STARD5 in cholesterol metabolism
• START proteins in non-vesicular cholesterol transport
• Index.