Systems Biology of RNA Binding Proteins

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Yeo, Gene W. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2014.
• Σειρά: Advances in Experimental Medicine and Biology, 825
• Θέματα: Life sciences.; Gene expression.; Proteins.; Systems biology.; Life Sciences.; Systems Biology.; Protein Science.; Gene Expression.

After transcription in the nucleus, RNA binding proteins (RBPs) recognize cis-regulatory RNA elements within pre-mRNA sequence to form mRNA-protein (mRNP) complexes. Similarly to DNA binding proteins such as transcription factors that regulate gene expression by binding to DNA elements in the promot...

Πίνακας περιεχομένων:

• Encyclopedia of RNA binding protein expression and domain annotations
• RNA localization and RNA binding proteins that control localization
• Genome-wide approaches to studying alternative polyadenylation events and the RBPs that control them
• RNA binding proteins, PRC complex and long ncRNAs
• Gene and genome regulation by piwi proteins
• Engineering Artificial RBP interactions
• Querying functional polymorphisms by high throughput binding and functional assays
• RNA binding protein networks in EMT/MET
• Therapies against diseases associated with RNA processing defects and RNA binding proteins
• Repeat-disorders and the RNA binding proteins implicated in them
• RNA binding proteins in heart development
• Identification of miRNAs and their targets in C elegans
• Splicing code
• Index.