Microglia in Health and Disease

• Corporate Author: SpringerLink (Online service)
• Other Authors: Tremblay, Marie-Ève (Editor), Sierra, Amanda (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2014.
• Subjects: Medicine.; Immunology.; Neurosciences.; Neurobiology.; Biomedicine.

These past few years have witnessed a revolution in our understanding of microglia, especially since their roles in the healthy central nervous system (CNS) have started to unravel. These cells were shown to actively maintain health, in concert with neurons and other types of CNS cells, providing fu...

Table of Contents:

• Introduction
• Historical Context
• Microglial Physiology
• Lessons from in vivo Imaging
• Roles in Immune Responses
• Neuroprotection Versus Neurotoxicity
• Developmental Neuronal Elimination
• Developmental Angiogenesis, Myelination and Astrogliogenesis
• Developing and Mature Synapses
• Adult Neurogenesis, Learning and Memory
• Neuropathic Pain
• Drug Addiction
• Aging
• Neurodevelopmental and Neuropsychiatric Disorders
• Human Immunodeficiency Virus
• Multiple Sclerosis
• Ischemia and Stroke
• Neurodegenerative Diseases
• Spinal Cord and Brain Trauma.