Tissue and Organ Regeneration in Adults Extension of the Paradigm to Several Organs /

• Κύριος συγγραφέας: Yannas, Ioannis V. (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2015.
• Έκδοση: 2nd ed. 2015.
• Θέματα: Engineering.; Biotechnology.; Dermatology.; Biomedical engineering.; Biomaterials.; Biomedical Engineering.

 This textbook describes the basic principles of induced organ regeneration in skin and peripheral nerves and extends the original successful paradigm to other organs. A set of trans-organ rules is established and its use in regeneration of several organs is illustrated from the works of several independent investigators who worked with a variety of organs, such as the lung, the bladder, and the Achilles tendon, using collagen-based scaffolds somewhat similar to the original one. These critical medical treatments fill the clinical need that is not met by organ transplantation. New to this second edition: New information extending the paradigm of tissue regeneration from organ regeneration in skin and peripheral nerves to other organs Guidelines, known as trans-organ rules, are described for the first time for extending this unique medical treatment to organs of several medical specialties The work serves as a comprehensive text and reference for students and practitioners of tissue engineering  . 

 The Irreversibility of Organ Injury -- Nonregenerative Tissues -- Experimental Methods I. The Anatomically Well-Defined Wound -- Experimental Methods II. The Defect Closure Rule -- Regeneration of Skin -- Regeneration of a Peripheral Nerve -- Minimum Reactants Required for Synthesis of Skin and Peripheral Nerves; Extension to Tissues of Other  Organs -- An Antagonistic Relation Between Wound Contraction and Regeneration -- Molecular biology of contraction blockade by active scaffolds -- The Scaffold Regeneration Paradigm and its Consequences.