Molecular Genetics of Pediatric Orthopaedic Disorders

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Wise, Carol A. (Επιμελητής έκδοσης), Rios, Jonathan J. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2015.
• Θέματα: Medicine.; Human genetics.; Orthopedics.; Biomedicine.; Human Genetics.; Biomedicine general.

In the past two decades we have seen a surge forward in understanding the genetics and biochemistry underlying many pediatric orthopaedic disorders. A few projects have even progressed into the realm of clinical trials that are primarily aimed at controlling progressive disease. Meanwhile, genomic t...

Πίνακας περιεχομένων:

• Overview of next generation, high-throughput molecular genetic methods
• Neurofibromin in skeletal development
• Molecular genetics of congenital multiple large joint dislocation
• DMP-1 in postnatal bone development
• The genetic architecture of idiopathic scoliosis
• Insights into the genetics of clubfoot
• Classification and etiologic dissection of vertebral segmentation anomalies
• Genetic and environmental interaction in malformation of the vertebral column
• Somatic mutations in overgrowth syndromes
• Index.