Gene Therapy for HIV and Chronic Infections

• Corporate Author: SpringerLink (Online service)
• Other Authors: Berkhout, Ben (Editor), Ertl, Hildegund C.J (Editor), Weinberg, Marc S. (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2015.
• Series: Advances in Experimental Medicine and Biology, 848
• Subjects: Medicine.; Gene therapy.; Immunology.; Biomedicine.; Gene Therapy.; Biomedicine general.

This volume examines gene therapy and gene transfer approaches to preventing or treating chronic virus infections, focusing on the Big Three viral pathogens- HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV).  It explores molecular antiviral strategies, including RNA interference, aptamer-si...

Table of Contents:

• Gene Therapies for Hepatitis C Virus
• Recent Advances in Use of Gene Therapy to Treat Hepatitis B Virus Infection
• U1interference (U1i) for antiviral approaches
• Gene therapy strategies to block HIV-1 replication by RNA interference
• HIV and Ribozymes
• Editing CCR5: a novel approach to HIV gene therapy
• Synthetic DNA approach to Cytomegalovirus vaccine/immune therapy
• Vector-mediated antibody gene transfer for infectious diseases
• HIV latency and the non-coding RNA therapeutic landscape
• C peptides as entry inhibitors for gene therapy
• Aptamer-siRNA chimeras for HIV       .