Genomic Elements in Health, Disease and Evolution Junk DNA /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Felekkis, Kyriacos (Επιμελητής έκδοσης), Voskarides, Konstantinos (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2015.
• Έκδοση: 1st ed. 2015.
• Θέματα: Medicine.; Human genetics.; Cell biology.; Developmental biology.; Biomedicine.; Human Genetics.; Cell Biology.; Developmental Biology.

This book provides a thorough review of various non-coding genomic elements and discusses in depth their role in health, disease and evolution. It begins with an exploration of non-coding RNA molecules miRNAs, piRNAs, LncRNAs and transposable elements as these moieties dominate the scientific litera...

Πίνακας περιεχομένων:

• MicroRNAs' function and role in evolution
• MicroRNAs and disease
• piRNAs: Transposon silencing and germ line development.-Long non-coding cRNAs
• Unveiling transposable elements function to enrich knowledge for human physiology and disease pathogenesis
• Copy number variation in human health, disease and evolution
• Mini- and micro-satellite markers in health, disease and evolution
• Intron biology, focusing on group II introns, the ancestors of spliceosomal introns.- Centromeres in health, disease and evolution.- Structure and functions of telomeres in organismal homeostasis and disease.- Proximal regulatory elements with emphasis on CpG rich regions.- Genomic analysis through high-throughput sequencing.