Regenerative Medicine for Degenerative Muscle Diseases

• Corporate Author: SpringerLink (Online service)
• Other Authors: Childers, Martin K. (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Humana Press, 2016.
• Series: Stem Cell Biology and Regenerative Medicine,
• Subjects: Life sciences.; Biotechnology.; Stem cells.; Life Sciences.; Stem Cells.

This book compiles and explores cutting-edge research in degenerative skeletal disorders, such as Duchenne muscular dystrophy and congenital myopathy, and new stem-cell based therapies and gene replacement therapy. Twelve expertly-authored chapters navigate the nuances of these treatments in an arra...

Table of Contents:

• Preface
• 1. Regenerative Medicine Approaches to Degenerative Muscle Diseases
• 2. An Overview of rAAV Vector Product Development for Gene Therapy
• 3. Gene Discovery in Congenital Myopathy
• 4. Stem Cell Transplantation for Degenerative Muscle
• 5. Spinal Cord Cellular Therapeutics Delivery:  Device Design Considerations
• 6. Patient Derived Induced Pluripotent Stem Cells Provide a Regenerative Medicine Platform for Duchenne Muscular Dystrophy Heart Failure
• 7. Overview of Chemistry, Manufacturing and Controls (CMC) for Pluripotent Stem Cell-Based Therapies
• 8. Regenerative Rehabilitation: Synergizing Regenerative Medicine Therapies with Rehabilitation for Improved Muscle Regeneration in Muscle Pathologies
• 9. Practical Nutrition Guidelines for Individuals with Duchenne Muscular Dystrophy
• 10. Identifying Beneficial Drug Therapies for Muscle Disease Using Zebrafish
• 11. The Use of miRNAs in Muscle Diseases
• 12 Canine Inherited Dystrophinopathies and Centronuclear Myopathies
• Index.