Effect of Spaceflight and Spaceflight Analogue Culture on Human and Microbial Cells Novel Insights into Disease Mechanisms /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Nickerson, Cheryl A. (Επιμελητής έκδοσης), Pellis, Neal R. (Επιμελητής έκδοσης), Ott, C. Mark (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2016.
• Έκδοση: 1st ed. 2016.
• Θέματα: Medicine.; Immunology.; Medical microbiology.; Infectious diseases.; Space sciences.; Biomedicine.; Medical Microbiology.; Infectious Diseases.; Extraterrestrial Physics, Space Sciences.

Many breakthroughs in biological research and translational healthcare advancements have been achieved by studying the response of biological systems to extreme environments. The spaceflight platform provides a unique environment where researchers can explore fundamental questions into cellular and...

Πίνακας περιεχομένων:

• Foreword
• Chronology of Key Spaceflight and Spaceflight Analogue Culture Experiments using Human and Microbial Cells
• Part I. The Principles and Translational Impact of Space Life Sciences Research
• Overview and Translational Impact of Space Cell Biology Research.- Principles of Analogue and True Microgravity Bioreactors for Tissue Engineering.- Immune Dysfunction in Spaceflight: An Integrative View.- Part II. Human and Cellular Investigations
• Biomedical Advances in Three Dimensions: An Overview of Human Cellular Studies in Space and Spaceflight Analogues.- Outpacing Infectious Disease:  Mimicking the Host-Pathogen Microenvironment.- Use of in vitro Cell Culture Models to Understand the Cellular and Molecular Basis of Immune Dysfunction during Spaceflight.- Using a Spaceflight Three-Dimensional Microenvironment to Probe Cancer-Stromal Interactions.- Skeletal Muscle Tissue Culture Under Spaceflight Conditions.- Microgravity and Microgravity Analogue Studies of Cartilage and Cardiac Tissue Engineering.- Part III. Microbial Investigations
• Microbial Investigations: Overview.- Using Spaceflight and Spaceflight-Analogue Culture for Novel Mechanistic Insight into Salmonella Pathogenesis.- Response of Pseudomonas aeruginosa to Spaceflight and Spaceflight Analogue Culture: Implications for Astronaut Health and the Clinic.- Cellular responses of Escherichia coli to Microgravity and Microgravity Analogue Culture.- Spaceflight and Spaceflight Analogue-Induced Responses in Gram Positive Bacteria.  .