Circulating Tumor Cells

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Cote, Richard J. (Επιμελητής έκδοσης), Datar, Ram H. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2016.
• Έκδοση: 1st ed. 2016.
• Σειρά: Current Cancer Research,
• Θέματα: Medicine.; Cancer research.; Biomedicine.; Cancer Research.

This volume provides the latest research on circulating tumor cells aimed for cancer researchers, scientists, and molecular oncologists. It presents the basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications as to how CTCs can be used in diagnostic bioma...

Πίνακας περιεχομένων:

• Preface
• Foreword
• Section I. Technologies for CTC Identification
• 1. Significance of Studying Circulating Tumor Cells
• 2. Affinity-Based Enrichment of Circulating Tumor Cells
• 3. Size-Based and Non-Affinity Based Microfluidic Devices for Circulating Tumor Cell Enrichment and Characterization
• 4. Molecular Assays for the Detection and Molecular Characterization of CTCs
• 5. Cancer Stem Cells and Circulating Tumor Cells Molecular Markers, Isolation Techniques and Clinical Implications
• Section II. Fundamental Studies of  CTC
• 6. Circulating Tumor Cells and Tumor Dormancy.- 7. Prevention of Conversion of Tumor Dormancy into Proliferative Metastases
• 8. Genesis of Circulating Tumor Cells through Epithelial-Mesenchymal Transition as a Mechanism for Distant Dissemination
• Section III. CTC Analysis
• 9. CTC Analysis FISH, ISH, Array-CGH and Other Molecular Assays
• 10. Genome-Wide Gene Copy Number Analysis of Circulating Tumor Cells
• 11. Perspectives on the Functional Characterization and In Vitro Maintenance of Circulating Tumor Cells
• 12. Prognostic Implications of CTC in Breast Cancer
• Section IV. Potential Clinical Applications of CTC
• 13. CTC in Advanced Breast Cancer Prognosis, Monitoring and Clinical Utility
• 14. Evolution of Metastatic Disease: The Need for Monitoring and Emerging Therapeutic Opportunities
• 15. CTC for Biomarker and Companion Diagnostic Development
• 16. Perspectives on Clinical Applications of CTCs
• Index.