Mitochondria and Cell Death

• Corporate Author: SpringerLink (Online service)
• Other Authors: Hockenbery, David M. (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Humana Press, 2016.
• Series: Cell Death in Biology and Diseases
• Subjects: Life sciences.; Cell cycle.; Cell membranes.; Apoptosis.; Life Sciences.; Membrane Biology.; Cell Cycle Analysis.

This volume examines the role of mitochondria in different types of cell death, including apoptotic and necrotic cell deaths. Topics discussed include mitochondrial outer membrane permeabilization (MOMP) and the permeability transition pore; core processes such as calcium handling, fission and fusio...

Table of Contents:

• Preface
• 1.Lethal and non-lethal functions of the permeability transition pore
• 2.Mitochondrial Calcium and Ischemia-Reperfusion Injury in Heart
• 3.Mislocalization of mitochondrial intermembrane space proteins
• 4.Bcl-2 protein interplay on the outer mitochondrial membrane
• 5.Remodeling of Mitochondria in Apoptosis
• 6.Physiologic and Pathologic Functions of Mitochondrial ROS
• 7.Mitochondrial Mutagenesis in Cancer
• 8.Mitochondrial UPR in cancer
• 9.Mitochondrial signaling
• 10.Mitochondria and antiviral immunity
• 11.Mitochondrial permeabilization from lethality to vitality
• Index.