Protein Tyrosine Phosphatases in Cancer

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Neel, Benjamin G. (Επιμελητής έκδοσης), Tonks, Nicholas K. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2016.
• Θέματα: Medicine.; Cancer research.; Posttranslational modification.; Cell biology.; Biomedicine.; Cancer Research.; Cell Biology.; Posttranslational Modification.

This book aims to bridge the gap in understanding how protein-tyrosine phosphatases (PTPs), which carry out the reverse reaction of tyrosine phosphorylation, feature in cancer cell biology. The expertly authored chapters will first review the general features of the PTP superfamily, including their...

Πίνακας περιεχομένων:

• 1 Introduction to the PTP Superfamily
• 2 Receptor PTPs in Cancer
• 3 Non-Receptor PTPs in Cancer
• 4 HP2
• 5 C-PTP
• 6 PTP1B
• 7 PTP-PEST
• 8 Dual Specificity Phosphatases in Cancer
• 9 Phosphatase-dependent roles for PTEN in Cancer
• 10 Phosphatase-independent roles for PTEN in Cancer
• 11 PRL family members in Cancer
• 12 Cdc25 family
• 13 PTPs, metabolism and cancer
• 14 PTPs, metabolism and cancer
• 15 Current status of PTP-based therapeutics
• 16 Summary and Perspective. .