Molecular and Cellular Mechanobiology

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Chien, Shu (Επιμελητής έκδοσης), Engler, Adam J. (Επιμελητής έκδοσης), Wang, Peter Yingxiao (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2016.
• Σειρά: Physiology in Health and Disease
• Θέματα: Medicine.; Human physiology.; Molecular biology.; Proteins.; Cell physiology.; Atomic structure.; Molecular structure.; Spectra.; Biomedicine.; Human Physiology.; Cell Physiology.; Atomic/Molecular Structure and Spectra.; Protein Science.; Molecular Medicine.

This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across differe...

Πίνακας περιεχομένων:

• Part 1. Mechanosensors
• The Primary Cilium as a Strain Amplifying Microdomain for Mechanotransduction at the Cell Membrane
• Vascular Endothelial Mechanosensors in Response to Fluid Shear Stress
• Cadherins in Mechanotransduction
• Perspectives of FRET Imaging to study Epigenetics and Mechanobiology in the Nucleus
• Part 2. Transducers
• Emerging Roles of YAP/TAZ in Mechanobiology
• Role of Rho GTPases in Mechanobiology
• Illuminating Cell Adhesion: Modern Microscopy Approaches to Study Integrin-Based Focal Adhesions
• Part 3. Epigenetic and Genetic Regulations in the Nucleus
• Mechanotransduction to Epigenetic Remodeling
• The Nuclear Lamina: From Mechano-Sensing in Differentiation to Cancer Cell Migration
• Role of Cell Geometry on Nuclear Mechanics, Chromosome Reorganization, and Gene Expression
• Part 4. Applications
• Mechanobiological Control of Cell Fate for Applications in Cardiovascular Regenerative Medicine
• Heart Valve Mechanobiology in Development and Disease
• Molecular and Cellular Mechanobiology of Cancer.