Polycystic Kidney Disease Translating Mechanisms into Therapy /

Polycystic Kidney Disease Translating Mechanisms into Therapy /

This comprehensive guide to polycystic kidney disease captures the growing knowledge of this common, potentially-fatal and hereditary disease. The first two sections of the book provide an overview of PKD gene structures, mutations and pathophysiologic mechanisms. This is followed by chapters focuse...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Cowley, Jr., Benjamin D. (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Bissler, John J. (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2018.
Έκδοση:1st ed. 2018.
Θέματα:
Nephrology.
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • PART 1. POLYCYSTIC KIDNEY DISEASE GENES & PROTEINS
  • 1. Classical Polycystic Kidney Disease (PKD): Gene Structures and Mutations and Protein Structures and Functions
  • 2. Bardet-Biedl Syndrome
  • 3. Cystic Kidney Diseases Associated with Increased Cancer Risk: Tuberous Sclerosis Complex, Von Hippel Lindau, and Birt Hogg Dubé
  • PART 2. POLYCYCSTIC KIDNEY DISEASE: MECHANISMS OF DISEASE
  • 4. Aberrant Cellular Pathways in PKD
  • 5. Cilia and Polycystic Kidney Disease
  • 6. The Role of Inflammation and Fibrosis in Cystic Kidney Disease
  • PART 3. CLINICAL FEATURES
  • 7. Imaging-based Diagnosis of Autosomal Dominant Polycystic Kidney Disease
  • 8. Renal Structural Involvement in Autosomal Dominant Polycystic Kidney Disease: Cyst Growth and Total Kidney Volume: Lessons from the Consortium for Radiologic Imaging of Polycystic Kidney Disease (CRISP)
  • 9. Renal Complications: Pain, Infection and Nephrolithiasis
  • 10. ADPKD Extrarenal Manifestations: Polycystic Liver Disease
  • 11. Extrarenal Manifestations of Autosomal Dominant Polycystic Kidney Disease
  • PART 4. CLINICAL TRIALS AND EMERGING THERAPIES
  • 12. Role of Renin- Angiotensin- Aldosterone System Inhibition in Autosomal Dominant Polycystic Kidney Disease
  • 13. Vasopressin Receptor Antagonism
  • 14. End-stage Renal Disease in Patients with Autosomal Dominant Polycystic Kidney Disease
  • 15. Polycystic Kidney Disease: Translating Mechanisms into Therapy Management of ADPKD Today.

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