Omics Approaches to Understanding Muscle Biology

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Burniston, Jatin George (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Chen, Yi-Wen (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer US : Imprint: Springer, 2019.
• Έκδοση: 1st ed. 2019.
• Σειρά: Methods in Physiology
• Θέματα: Human physiology.; Proteomics.; Metabolism.; Human genetics.; Systems biology.; Human Physiology.; Metabolomics.; Human Genetics.; Systems Biology.

This book is a collection of principles and current practices in omics research, applied to skeletal muscle physiology and disorders. The various sections are categorized according to the level of biological organization, namely, genomics (DNA), transcriptomics (RNA), proteomics (protein), and metab...

Πίνακας περιεχομένων:

• Part I: Genomic and Epi-genomic
• 1) GWAS/muscle function and diseases (by Eric Hoffman)
• 2) Whole genome and whole exon sequencing/muscle disorders (by Silvère van der Maarel and Richard Lemmers)
• 3) Epi-genome approaches/muscle regeneration (by Vittorio Sartorelli)
• Part II: Transcriptomic
• 4) RNA profiling (by Yi-Wen Chen, confirmed)
• 5) miRNA profiling (by Alyson Fiorillo)
• 6) Single cell profiling in muscle (byPier Lorenzo Puri)
• 7) Statistics and bioinformatics (by Heather Gordish)
• Part III: Proteomic
• 8). Proteome profiling of human/ clinical samples - i.e. necessarily label-free techniques (by Lawrence Mandarino)
• 9) Proteome profiling of cell and animal models - i.e. label techniques such as SILAC (by Matthias Mann OR SILAM with JR Yates III)
• 10) Global analysis of post-translational modifications (by David E James)
• 11) Proteome dynamics - synthesis and degradation on a proteome wide scale (by Jatin Burniston, confirmed)
• Part IV: Metabolomic
• 12) Non-targeted metabolomics using mass spectrometry (by Charles Burant).