Cell Signaling in Vascular Inflammation

Although inflammatory disease of the vascular bed of the lung is a major cause of morbidity and mortality in both adult and pediatric age groups, the importance of vascular biology to its understanding, and in developing novel therapeutics, has been overlooked. In Cell Signaling in Vascular Inflamma...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Bhattacharya, Jahar (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Totowa, NJ : Humana Press, 2005.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
LEADER 03600nam a22004095i 4500
001 978-1-59259-909-7
003 DE-He213
005 20151204153430.0
007 cr nn 008mamaa
008 100301s2005 xxu| s |||| 0|eng d
020 |a 9781592599097  |9 978-1-59259-909-7 
024 7 |a 10.1007/978-1-59259-909-7  |2 doi 
040 |d GrThAP 
050 4 |a RD598.5-598.7 
072 7 |a MNJ  |2 bicssc 
072 7 |a MED085050  |2 bisacsh 
082 0 4 |a 617.413  |2 23 
245 1 0 |a Cell Signaling in Vascular Inflammation  |h [electronic resource] /  |c edited by Jahar Bhattacharya. 
264 1 |a Totowa, NJ :  |b Humana Press,  |c 2005. 
300 |a XII, 222 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 |a Heme Oxygenase-1 and Carbon Monoxide in Vascular Regulation -- Tumor Necrosis Factor-?/Receptor Signaling Through the Akt Kinase -- Protein Modifications by Nitric Oxide and Reactive Nitrogen Species -- Redox Signaling in Hypoxic Pulmonary Vasoconstriction -- cGMP-Dependent Protein Kinase in Regulation of the Perinatal Pulmonary Circulation -- Glutamate Receptor Activation in the Pathogenesis of Acute Lung Injury -- Carboxyl Methylation of Small GTPases and Endothelial Cell Function -- Pressure-Induced Inflammatory Signaling in Lung Endothelial Cells -- Regulation of Endothelial Barrier Function -- Sphingolipid Signaling -- Regulation of Cytokine Signaling -- Cell Signaling by Vasoactive Agents -- Reactive Oxygen Species and Cell Signaling in Lung Ischemia -- Pulmonary Vascular Barrier Regulation by Thrombin and Edg Receptors -- Second-Messenger Signaling in Lung Capillaries -- Plasma Membrane-to-Nucleus Calcium Signaling -- Signaling by Mitochondria -- Pro-Inflammatory Signaling by Endothelial Focal Complexes in Lung -- Hydrogen Peroxide As Intracellular Messenger -- Calcium-Inhibited Adenylyl Cyclase (AC6) Controls Endothelial Cell Barrier Function. 
520 |a Although inflammatory disease of the vascular bed of the lung is a major cause of morbidity and mortality in both adult and pediatric age groups, the importance of vascular biology to its understanding, and in developing novel therapeutics, has been overlooked. In Cell Signaling in Vascular Inflammation, leading basic and clinical researchers review the signal transduction mechanisms responsible for lung inflammation, including vascular hyperpermeability, white cell accumulation, and vascular remodeling. The authors cut across disciplines to bring together a broad-based presentation of inflammatory challenge, both in the initial phases of the inflammatory response, as well as in the more prolonged phase of genomic involvement. Authoritative and state-of-the-art, Cell Signaling in Vascular Inflammation offers physiologists, molecular and cell biologists, and pharmaceutical scientists a comprehensive survey of the signal transduction pathways in lung vascular cells that illuminates not only the processes of lung inflammation, but also the potential for developing new therapeutic strategies to combat inflammatory lung disease. 
650 0 |a Medicine. 
650 0 |a Vascular surgery. 
650 1 4 |a Medicine & Public Health. 
650 2 4 |a Vascular Surgery. 
700 1 |a Bhattacharya, Jahar.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9781588295255 
856 4 0 |u http://dx.doi.org/10.1007/978-1-59259-909-7  |z Full Text via HEAL-Link 
912 |a ZDB-2-SME 
950 |a Medicine (Springer-11650)