The G Protein-Coupled Receptors Handbook
G protein-coupled receptors (GPCRs) are involved in many processes in the human body relevant to health and disease, and consequently are the targets of approximately 70% of pharmacological therapeutics and a major source of new drug candidates. In The G Protein-Coupled Receptors Handbook, leading a...
| Συγγραφή απο Οργανισμό/Αρχή: | |
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| Άλλοι συγγραφείς: | |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Totowa, NJ :
Humana Press,
2005.
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| Σειρά: | Contemporary Clinical Neuroscience
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| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- GPCRs: Structure and Function
- Structure—Function Relationships in G Protein-Coupled Receptors
- Molecular Mechanisms Involved in the Activation of Rhodopsin-Like Seven-Transmembrane Receptors
- GPCR Folding and Maturation
- Regulated Membrane Trafficking and Proteolysis of GPCRs
- GPCR Activity and Its Regulators
- Heterotrimeric G Proteins and Their Effector Pathways
- RGS Proteins
- G Protein-Coupled Receptor Kinases
- Regulators of GPCR Activity
- GPCR Interacting Proteins
- GPCR Dimerization/Oligomerization
- Biophysical and Biochemical Methods to Study GPCR Oligomerization
- Oligomerization Domains of G Protein-Coupled Receptors
- Functional Complementation and the Analysis of GPCR Dimerization
- The Role of Oligomerization in G Protein-Coupled Receptor Maturation
- Receptor Oligomerization and Trafficking
- Modulation of Receptor Pharmacology by G Protein-Coupled Receptor Dimerization
- Recent Developments in Drug Discovery
- Role of Heteromeric GPCR Interactions in Pain/Analgesia
- Conformational Plasticity of GPCR Binding Sites
- De-Orphanizing GPCRs and Drug Development.
