| Περίληψη: | Although squamous cell head and neck cancer is not the most common cancer in the United States, it is an important and disabling malignancy that-through the advances recently achieved by multiple medical disciplines-serves as a model of multimodality solid tumor management. In Squamous Cell Head and Neck Cancer: Recent Clinical Progress and Prospects for the Future, leading expert physicians and investigators from around the world review the state of the art in the management of squamous cell head and neck cancer, with emphasis on coordinating different treatment modalities. The authors address several surgical issues, including laser-based surgery, larynx preservation approaches, salvage surgery, and neck management after non-operative treatment. They also discuss definitive radiation for larynx cancer, brachytherapy, altered fractionation radiation, intensity modulated radiation therapy, and the importance of tumor hypoxia, as well as the role of chemotherapy in sequential, concurrent, and adjuvant multimodality treatment schedules. Other topics of special interest include targeted and gene therapies, multimodality management of nasopharyngeal cancer, chemoprevention, toxicity modification, quality of life outcomes, symptom palliation, and epidemiology. Comprehensive and authoritative, Squamous Cell Head and Neck Cancer: Recent Clinical Progress and Prospects for the Future offers head and surgeons, radiation oncologists, and medical oncologists an interdisciplinary review of recent successes on multiple fronts in the treatment of this disease, as well as a blueprint for future investigation.
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