The Serotonin Receptors From Molecular Pharmacology to Human Therapeutics /

The recent cloning and identification of a large number of serotonin (5-HT) receptors-a major family of therapeutic targets-holds out the possibility of developing novel, subtype-selective 5-HT receptor agonists and antagonists for use as psychiatric, cardiovascular, and neurological medications. In...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Roth, Bryan L. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Totowa, NJ : Humana Press, 2006.
Σειρά:The Receptors
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Molecular Biology and Genomic Organization of G Protein-Coupled Serotonin Receptors
  • Structure and Function Reveal Insights in the Pharmacology of 5-HT Receptor Subtypes
  • Polymorphic and Posttranscriptional Modifications of 5-HT Receptor Structure
  • Strategies for the Development of Selective Serotonergic Agents
  • 5-HT Receptor Signal Transduction Pathways
  • Agonist-Directed Trafficking of 5-HT Receptor-Mediated Signal Transduction
  • Identification of 5-HT2 and 5-HT4 Receptor-Interacting Proteins
  • 5-HT Receptor-Associated Proteins (FRAPs)
  • Cellular and Subcellular Localization of Serotonin Receptors in the Central Nervous System
  • Chemical Neuroanatomy of 5-HT Receptor Subtypes in the Mammalian Brain
  • Modulation of the Neuronal Activity and Neurotransmitter Release by 5-HT1A and 5-HT1B/1D Receptors
  • Electrophysiology of 5-HT2A Receptors and Relevance for Hallucinogen and Atypical Antipsychotic Drug Actions
  • The Emergence of 5-HT2B Receptors as Targets to Avoid in Designing and Refining Pharmaceuticals
  • The 5-HT3 Receptor
  • 5-HT3 and 5-HT4 Receptors as Targets for Drug Discovery for Dementia
  • Electrophysiological Properties of G?s-Coupled 5-HT Receptors (5-HT4, 5-HT6, 5-HT7)
  • 5-HT6 Receptors as Targets for the Treatment of Cognitive Deficits in Schizophrenia
  • 5-HT7 Receptors as Favorable Pharmacological Targets for Drug Discovery
  • Serotonin System Gene Knockouts
  • Effects of Serotonin-Related Gene Deletion on Measures of Anxiety, Depression, and Neurotransmission.