Reverse Transcriptase Inhibitors in HIV/AIDS Therapy

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: St.Georgiev, Vassil (Επιμελητής έκδοσης), Skowron, Gail (Επιμελητής έκδοσης), Ogden, Richard (Επιμελητής έκδοσης), Lange, Joep M. A. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Totowa, NJ : Humana Press, 2006.
• Σειρά: Infectious Disease
• Θέματα: Medicine.; Infectious diseases.; Medicine & Public Health.; Infectious Diseases.

Despite significant pharmacological advances, the backbone of the most highly active antiretroviral therapy regimens for controlling HIV/AIDS is still a combination of reverse transcriptase inhibitors (RTIs) first discovered in the late 1980s. In Reverse Transcriptase Inhibitors in HIV/AIDS Therapy,...

Πίνακας περιεχομένων:

• Structural Studies on HIV Reverse Transcriptase Related to Drug Discovery
• Zidovudine, Lamivudine, and Abacavir
• Stavudine, Didanosine, and Zalcitabine
• Emtricitabine
• Nucleotide Analogs
• Resistance to Nucleoside and Nucleotide Reverse Transcriptase Inhibitors
• Pharmacokinetics of Reverse Transcriptase Inhibitors
• Peripheral Neuropathy Associated With Nucleoside Reverse Transcriptase Inhibitor Therapy
• Mitochondrial Dysfunction and Nucleoside Reverse Transcriptase Inhibitor Therapy
• Mitochondrial Toxicity and Lipodystrophy
• Nevirapine
• Efavirenz
• Delavirdine
• Resistance to Non-Nucleoside Reverse Transcriptase Inhibitors
• Vertical Transmission of HIV and Therapeutic Interventions
• New Reverse Transcriptase Inhibitors in Development
• Antiretroviral Drugs for Millions.