Gene Therapy for Cancer

The possibility of treating cancer, a disease defined by genetic defects, by introducing genes targeting these very alterations has led to an immense interest in gene therapy for cancer. Although incremental successes have been realized, enthusiasm for gene therapy has declined due to an increasing...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Hunt, Kelly K. (Επιμελητής έκδοσης), Vorburger, Stephan A. (Επιμελητής έκδοσης), Swisher, Stephen G. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Totowa, NJ : Humana Press, 2007.
Σειρά:Cancer Drug Discovery and Development
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Vectors
  • Adenovector-Mediated Cancer Gene Therapy
  • Efficacy, Toxicity, and Immunogenicity of Adenoviral Vectors
  • Lentiviral and Retroviral Vector Systems
  • Vaccinia and Pox-Virus
  • Herpes Simplex Virus as a Therapy for Cancer
  • Alphavirus Vectors for Gene Therapy Applications
  • Vesicular Stomatitis Virus and RNA Viruses as Gene Therapy Vectors
  • Parvovirus Vectors
  • Nonviral Vector Systems
  • Gene Therapy Approaches
  • Oncogenes, Tumor Suppressor Genes and Apoptosis-Inducing Genes Utilized in Cancer Gene Therapy
  • Gene Silencing Therapy Against Cancer
  • Tumor Targeting-Retargeted Adenovirus
  • Oncolytic Herpes Simplex for Gene Therapy in Preclinical and Clinical Trials
  • Cytokine Gene Therapy for Genitourinary Cancer
  • Combination of Gene Therapy with Radiation
  • Gene Transfer for Chemoprotection and Enrichment of Hematopoietic Stem Cells
  • Nonviral Genetic Vaccines for Cancer
  • Gene Therapy Targeted at Angiogenesis and Lymphangiogenesis for Cancer Treatment
  • Tumor-Specific Replicating Adenoviruses
  • Clinical Applications
  • Problems, Side Effects, and Disappointments in Clinical Cancer Gene Therapy
  • Trials and Tribulations in Developing Clinical Trials of Gene Therapy
  • Phase I Clinical Experience with Intravenous Administration of PV701, an Oncolytic Virus
  • MDA-7/IL-24 as a Multi-Modality Therapy for Cancer
  • Development of Therapeutic Genes for Breast Cancer Treatment
  • Steps in a Translational Cancer Gene Therapy Trial.