Regulation of Gene Expression Molecular Mechanisms /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Perdew, Gary H. (Editor), Heuvel, John P. Vanden (Editor), Peters, Jeffrey M. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Totowa, NJ : Humana Press, 2007.
• Subjects: Life sciences.; Human genetics.; Pharmacology.; Biochemistry.; Life Sciences.; Biochemistry, general.; Pharmacology/Toxicology.; Human Genetics.

Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advan...

Table of Contents:

• Gene Expression Control At The Mrna Level
• Overview
• Messenger RNA Accumulation
• Transcript Profiling
• Transcriptional Regulation of Gene Expression
• Posttranscriptional Processing of Messenger RNA
• Regulation Of Protein Levels And Transcription Factor Function
• Overview
• Protein Synthesis and Turnover
• Proteomics
• Determination of Protein-Protein Interactions and the Motifs That Mediate Them
• Posttranslational Modifications
• Dissection of Signaling Pathways
• Use Of Transgenic And Knockout Mice To Study Gene Regulation
• Overview
• Production of Transgenic Animals
• Knockout Animals
• Isolation of Cells and Cell Lines From Transgenic and Knockout Animals.