Molecular Targeting in Oncology

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Kaufman, Howard L. (Επιμελητής έκδοσης), Wadler, Scott (Επιμελητής έκδοσης), Antman, Karen (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Totowa, NJ : Humana Press, 2008.
• Σειρά: Cancer Drug Discovery and Development
• Θέματα: Medicine.; Cancer research.; Pharmacology.; Medicinal chemistry.; Oncology.; Biomedicine.; Cancer Research.; Pharmacology/Toxicology.; Medicinal Chemistry.

In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application. The volume covers the complexity of the rapidly developing area of targeted therapies for the treatment of patients with canc...

Πίνακας περιεχομένων:

• General Strategies for Molecular Targeting in Oncology
• The Cell Cycle
• mTOR
• Ras/Raf/MEK Inhibitors
• 17-AAG
• The Cancer Epigenome
• Molecular Targeting for Specific Disease Sites
• Molecular Targeting in Upper Gastrointestinal Malignancies
• Molecular Targeting of Colorectal Cancer
• Molecular Targeting in Hepatocellular Carcinoma
• Molecularly Targeted Therapy in Pancreatic Cancer
• Untargeted Use of Targeted Therapy
• Renal Cell Carcinoma
• Targeted Therapies for Prostate Cancer
• Molecular Targets in Ovarian Cancer and Endometrial Cancer
• Targeted Therapy For Breast Cancer
• Melanoma
• Classes of Drugs for Molecular Targeting in Oncology
• Antibody Therapy of Cancer
• Nucleic Acid Therapies for Cancer Treatment
• Engineering Oncolytic Measles Viruses for Targeted Cancer Therapy
• Vaccines as Targeted Cancer Therapy
• Cytokine-Based Therapy for Cancer
• Cyclooxygenase-2 as a Target for Cancer Prevention and Treatment
• Specific Drugs for Molecular Targeting in Oncology
• Imatinib Mesylate (Gleevec®) and the Emergence of Chemotherapeuticss Drug-Resistant Mutations
• Development of a Targeted Treatment for Cancer
• VEGF Inhibition for Cancer Therapy
• Somatostatin Analogue Therapy
• Challenges in Molecular Targeting in Oncology
• Patient Selection for Rational Development of Novel Anticancer Agents
• Clinical Trial Design with Targeted Agents
• How to Define Treatment Success or Failure if Tumors Do Not Shrink
• Molecular Imaging in Oncology
• Combinations of Molecular-Targeted Therapies
• Preclinical Development of Molecularly Targeted Agents in Oncology.