The Dopamine Receptors

• Corporate Author: SpringerLink (Online service)
• Other Authors: Neve, Kim A. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Totowa, NJ : Humana Press : Imprint: Humana Press, 2010.
• Series: The Receptors
• Subjects: Medicine.; Human physiology.; Neurosciences.; Pharmacology.; Pharmaceutical technology.; Neurology.; Neurobiology.; Medicine & Public Health.; Pharmacology/Toxicology.; Human Physiology.; Pharmaceutical Sciences/Technology.

Dopamine receptors are among the most validated drug targets for neuropsychiatric disorders such as schizophrenia and Parkinson’s disease, and are potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. The new kno...

Table of Contents:

• Historical Overview: Introduction to the Dopamine Receptors
• Gene and Promoter Structures of the Dopamine Receptors
• Structural Basis of Dopamine Receptor Activation
• Dopamine Receptor Subtype-Selective Drugs: D1-Like Receptors
• Dopamine Receptor Subtype-Selective Drugs: D2-Like Receptors
• Dopamine Receptor Signaling: Intracellular Pathways to Behavior
• Dopaminergic Modulation of Glutamatergic Signaling in Striatal Medium Spiny Neurons
• Regulation of Dopamine Receptor Trafficking and Responsiveness
• Dopamine Receptor-Interacting Proteins
• Dopamine Receptor Oligomerization
• Dopamine Receptor Modulation of Glutamatergic Neurotransmission
• Unraveling the Role of Dopamine Receptors In Vivo: Lessons from Knockout Mice
• Dopamine Receptors and Behavior: From Psychopharmacology to Mutant Models
• Dopamine Modulation of the Prefrontal Cortex and Cognitive Function
• In Vivo Imaging of Dopamine Receptors
• Dopamine Receptors and the Treatment of Schizophrenia
• Dopamine Receptor Subtypes in Reward and Relapse
• Dopamine Receptors and the Treatment of Parkinson’s Disease
• Dopamine Receptor Genetics in Neuropsychiatric Disorders.