Breast Cancer in the Post-Genomic Era

• Corporate Author: SpringerLink (Online service)
• Other Authors: Giordano, Antonio (Editor), Normanno, Nicola (Editor)
• Format: Electronic eBook
• Language: English
• Published: Totowa, NJ : Humana Press, 2009.
• Series: Current Clinical Oncology
• Subjects: Medicine.; Oncology.; Pathology.; Surgical oncology.; Medicine & Public Health.; Surgical Oncology.

Breast Cancer is the most common tumor in women and it is the second leading cause of cancer deaths worldwide. Due to breakthroughs in gene profiling, the knowledge of the pathophysiology of the mammary gland had greatly increased over the last decade. In Breast Cancer in the Post Genomic Era, Anton...

Table of Contents:

• The Genomic Basis of Breast Development and Differentiation
• Mammary Glands, Stem Cells and Breast Cancer
• The Genetics of Breast Cancer
• Alterations in Cell Cycle Regulatory Genes in Breast Cancer
• Neuregulins in the Nucleus
• Role of the EGF-CFC Family in Mammary Gland Development and Neoplasia
• Modeling Human Breast Cancer
• Gene Expression Profiling in Breast Cancer
• TGF-? Signaling
• DNA Methylation in Breast Cancer
• Signal Transduction Inhibitors in the Treatment of Breast Cancer
• Integration of Target-Based Agents in Current Protocols of Breast Cancer Therapy.