5-HT2C Receptors in the Pathophysiology of CNS Disease

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Di Giovanni, Giuseppe (Επιμελητής έκδοσης), Esposito, Ennio (Επιμελητής έκδοσης), Di Matteo, Vincenzo (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Totowa, NJ : Humana Press : Imprint: Humana Press, 2011.
• Σειρά: The Receptors ; 22
• Θέματα: Medicine.; Human physiology.; Neurosciences.; Pharmacology.; Neurology.; Neurobiology.; Biomedicine.; Pharmacology/Toxicology.; Human Physiology.

Research of 5-HT2c receptors stretches back twenty-five years, and while much of it has been productive, the past decade of research has been extraordinary in terms of both amount produced and insights gained. It is hardly surprising that 5-HT2c receptor research has grown so fruitful, given that it...

Πίνακας περιεχομένων:

• The making of the 5-HT2C receptor
• Serotonin 5-HT2C receptors: chemical neuronatomy in the mammalian brain
• The medicinal chemistry of 5-HT2C receptor ligands
• Insights into 5-HT2C receptor function gained from transgenic mouse models
• Serotonin 5-HT2C receptor signal transduction
• Homology modeling of 5-HT2C receptors
• 5-HT2C receptor dimerization
• RNA editing of 5-HT2C receptor and neuropsychiatric diseases
• Serotonergic control of adult neurogenesis: focus on 5-HT2C receptors
• The constitutive activity of 5-HT2C receptors as an additional modality of interaction of the serotonergic system
• The 5-HT2C receptor subtype controls central dopaminergic systems: evidence from electrophysiological and neurochemical studies
• The role of serotonin-2C receptors in the pathophysiology of depression
• 5-HT2C receptors and suicidal behaviour
• The 5-HT2C receptor as a target for schizophrenia
• Serotonin and reward-related behaviour: focus on 5-HT2C receptors
• Tat-3L4F: a novel peptide for treating drug addiction by disrupting interaction between PTEN and 5-HT2C receptor
• The role of serotonin in eating behaviour: focus on 5-HT2C receptors
• Physiological and pathophysiological aspects of 5-HT2C receptors in basal ganglia
• Modeling tardive dyskinesia: predictive 5-HT2C receptor antagonist treatment
• The role of 5-HT2A/2C receptors in sleep and waking
• Role of alternative splicing of the 5-HT2C in the Prader-Willi syndrome
• The role of 5-HT2C receptor in epilepsy
• The role of serotonin on attentional processes and executive functioning: focus on 5-HT2C receptors
• 5-HT2C receptors in learning
• The role of 5-HT2C polymorphisms in behavioural and psychological symptoms of alzheimer's disease
• Ocular hypotension: involvement of serotonergic 5-HT2C receptors.