Nuclear Reprogramming and Stem Cells

Research into the field of stem cell biology has developed exponentially over recent years, and is beginning to offer significant promise for unravelling the molecular basis of a multitude of disease states. Importantly, in addition to offering the opportunity to delve deeply into the mechanisms tha...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Ainscough, Justin (Επιμελητής έκδοσης), Yamanaka, Shinya (Επιμελητής έκδοσης), Tada, Takashi (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Totowa, NJ : Humana Press : Imprint: Humana Press, 2012.
Σειρά:Stem Cell Biology and Regenerative Medicine
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Introduction by John Gurdon and Azim Surani
  • Introduction by Ian Wilmut
  • Inherent Nuclear Reprogramming in Mammalian Embryos
  • Epigenetic Reprogramming During Somatic Cell Nuclear Transfer and the Development of Primordial Germ Cells
  • Epigenetic Reprogramming with Oocyte Molecules
  • Cell Fusion-Mediated Nuclear Reprogramming of Somatic Cells
  • Generation of Induced Pluripotent Stem Cells from Somatic Cells
  • The Consequences of Reprogramming a Somatic Cell for Mitochondrial DNA Transmission, Inheritance and Replication
  • The Function of Nanog in Pluripotency
  • The Function of Oct3/4 and Sox2 in Pluripotency
  • Generation of Neural Cells from Pluripotent Stem Cells
  • Non-Cell Autonomous Reprogramming Towards a Pluripotent State
  • Towards Regeneration of Retinal Function Using Pluripotent Stem Cells
  • Reprogramming Towards Pancreatic beta-Cells
  • Pancreatic Plasticity and Reprogramming – Novel Directions Towards Disease Therapy
  • Phenotype and Developmental Potential of Cardiomyocytes from Induced Pluripotent Stem Cells and Human Embryonic Stem Cells
  • The Generation of Disease Specific Cell Lines and Their Use for Developing Drug Therapies
  • Advances in the Culture of Human Embryonic Stem Cells
  • Culture adaptation of pluripotent stem cells: challenges and opportunities
  • Epilogue.