Cytoskeleton and Human Disease

• Corporate Author: SpringerLink (Online service)
• Other Authors: Kavallaris, Maria (Editor)
• Format: Electronic eBook
• Language: English
• Published: Totowa, NJ : Humana Press : Imprint: Humana Press, 2012.
• Subjects: Life sciences.; Cancer research.; Biochemistry.; Cell biology.; Cell cycle.; Cell physiology.; Life Sciences.; Cell Biology.; Cell Cycle Analysis.; Cell Physiology.; Biochemistry, general.; Cancer Research.

The cytoskeleton is made up of a large variety of specialized proteins and is a highly dynamic system that is involved in the majority of key cellular events. It is now clear that the cytoskeleton is often associated, and has diverse roles in human disease.  Emerging understanding of the molecular a...

Table of Contents:

• Actin
• Microtubules
• The Kinesin Superfamily
• Myosins
• The Actin Cytoskeleton and Membrane Organisation in T Lymphocytes
• Thin Filament Disease of Stricted Muscle
• Filamin and disease
• LIMK and Cancer Metastasis
• Actin Mutations and Deafness
• Therapeutic Targeting of the Actin Cytoskeleton
• Microtubules as a Target in Cancer Therapy
• Microtubules and drug resistance
• Posttranslational Modifications of Tubulin
• Stathmin and Cancer
• The Biology and Pathobiology of Tau Protein
• Tubulin-Related Malformations of Cortical Development
• Spectrins in Human Diseases
• Laminopathies
• Desmin and Heart Disease
• Neurodegenerative Diseases and Intermediate Filaments.