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03591nam a22006255i 4500 |
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978-1-907673-94-8 |
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DE-He213 |
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20151204144317.0 |
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cr nn 008mamaa |
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140528s2013 xxk| s |||| 0|eng d |
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|a 9781907673948
|9 978-1-907673-94-8
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|a 10.1007/978-1-907673-94-8
|2 doi
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|a RC254-282
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|a MED062000
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|a 616.994
|2 23
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|a Alvarez, Ricardo H.
|e author.
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|a Handbook of HER2-targeted agents in breast cancer
|h [electronic resource] /
|c by Ricardo H Alvarez, Javier Cortés, Leticia De Mattos-Arruda, Mary Falzon, Angelica Fasolo, Michael Gandy, Luca Gianni, Nadia Harbeck, Martine Piccart, Stefania Zambelli, Dimitrios Zardavas.
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|a Tarporley :
|b Springer Healthcare Ltd. :
|b Imprint: Springer Healthcare,
|c 2013.
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| 300 |
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|a XI, 96 p. 13 illus.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a text file
|b PDF
|2 rda
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|a Introduction and background biology -- HER2 testing -- HER2-positive breast cancer: adjuvant and neoadjuvant therapy -- HER2-positive metastatic breast cancer: first-line treatment -- HER2-positive metastatic breast cancer: second-line treatment -- Emerging targeted agents for HER2-positive breast cancer.
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|a Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year. Of these cases, approximately 15–25% overexpress HER2, a transmembrane RTK kinase that is associated with aggressive tumor growth and poor outcomes. However, in the past decade, survival rates of patients with HER-positive breast cancer have significantly improved due to increased screening, HER2 testing, and breakthrough HER2-targeted drug therapies. Handbook of HER2-Targeted Agents in Breast Cancer provides oncologists, primary care physicians, trainees and other healthcare providers with a concise, accessible, and up-to-date survey of the field, including a review of our current understanding of the biology of the HER2 pathway and the rationale for targeting it in early-stage and advanced breast cancer, an overview of HER2-testing, and evidence-based discussions of available HER2-targeted regimens in the adjuvant and metastatic settings.
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|a Medicine.
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|a General practice (Medicine).
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|a Internal medicine.
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|a Oncology.
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|a Primary care (Medicine).
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|a Pharmacotherapy.
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|a Medicine & Public Health.
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|a Oncology.
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|a Primary Care Medicine.
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|a General Practice / Family Medicine.
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| 650 |
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|a Internal Medicine.
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| 650 |
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|a Pharmacotherapy.
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| 700 |
1 |
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|a Cortés, Javier.
|e author.
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| 700 |
1 |
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|a Mattos-Arruda, Leticia De.
|e author.
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| 700 |
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|a Falzon, Mary.
|e author.
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| 700 |
1 |
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|a Fasolo, Angelica.
|e author.
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| 700 |
1 |
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|a Gandy, Michael.
|e author.
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| 700 |
1 |
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|a Gianni, Luca.
|e author.
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| 700 |
1 |
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|a Harbeck, Nadia.
|e author.
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| 700 |
1 |
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|a Piccart, Martine.
|e author.
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| 700 |
1 |
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|a Zambelli, Stefania.
|e author.
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| 700 |
1 |
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|a Zardavas, Dimitrios.
|e author.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
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|t Springer eBooks
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| 776 |
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8 |
|i Printed edition:
|z 9781907673931
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| 856 |
4 |
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|u http://dx.doi.org/10.1007/978-1-907673-94-8
|z Full Text via HEAL-Link
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| 912 |
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|a ZDB-2-SME
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| 950 |
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|a Medicine (Springer-11650)
|
