mTOR Inhibition for Cancer Therapy: Past, Present and Future

• Corporate Author: SpringerLink (Online service)
• Other Authors: Mita, Monica (Editor), Mita, Alain (Editor), Rowinsky, Eric K. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Paris : Springer Paris : Imprint: Springer, 2016.
• Edition: 1st ed. 2016.
• Subjects: Medicine.; Molecular biology.; Hematology.; Oncology.; Medicine & Public Health.; Molecular Medicine.

This book describes the challenges involved in developing mTOR inhibitors for cancer treatment, starting with an in-depth examination of their molecular mechanism of action, with emphasis on the class side-effects, efficacy and mechanisms of resistance, as well as on promising novel directions for t...