HIV-1 Latency

• Corporate Author: SpringerLink (Online service)
• Other Authors: Silvestri, Guido (Editor, http://id.loc.gov/vocabulary/relators/edt), Lichterfeld, Mathias (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: Current Topics in Microbiology and Immunology, 417
• Subjects: Immunology.; Virology.; Pathology.; Epidemiology.

This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and...

Table of Contents:

• Molecular Control of HIV and SIV Latency
• Assays to Measure Latency, Reservoirs and Reactivation
• The Antiviral Immune Response and its Impact on the HIV-1 Reservoir
• Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiretroviral Therapy
• SIV Latency in Macrophages in the CNS
• Mathematical models of HIV latency
• Residual Immune Activation and Latency
• Immune Interventions to Eliminate the HIV Reservoir
• Cell and Gene Therapy for HIV Cure.