Mechanisms of Drug Resistance in Cancer Therapy

• Corporate Author: SpringerLink (Online service)
• Other Authors: Mandalà, Mario (Editor, http://id.loc.gov/vocabulary/relators/edt), Romano, Emanuela (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Series: Handbook of Experimental Pharmacology, 249
• Subjects: Pharmacology.; Cancer research.; Drug resistance.; Molecular biology.; Pharmacology/Toxicology.; Cancer Research.; Drug Resistance.; Molecular Medicine.
• Physical Description: VIII, 297 p. 32 illus., 31 illus. in color. online resource.
• ISBN: 9783030105075
• ISSN: 0171-2004 ;
• DOI: 10.1007/978-3-030-10507-5

A major objective of this book is to reveal unprecedented opportunities to understand and overcome drug resistance through the clinical assessment of rational therapeutic drug combinations and the use of predictive and prognostic biomarkers to enable patient stratification and tailor treatments. It offers to the readers an updated overview on the possible reasons of failure of new and promising therapeutic opportunities.