Molecular and Cell Biology of Cancer When Cells Break the Rules and Hijack Their Own Planet /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Fior, Rita (Editor, http://id.loc.gov/vocabulary/relators/edt), Zilhão, Rita (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Series: Learning Materials in Biosciences,
• Subjects: Cancer research.; Human genetics.; Molecular biology.; Cell biology.; Metabolism.; Cancer Research.; Human Genetics.; Molecular Medicine.; Cell Biology.; Metabolomics.

This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent ch...

Table of Contents:

• Preface
• Molecular and Cell Biology of Cancer when cells break the rules and hijack their own planet
• Cancer as an Evolutionary Process
• Cell signaling in cancer
• The cell cycle, cytoskeleton and cancer
• Genomic Instability: DNA Repair and Cancer
• Cell metabolism in cancer - an energetic switch
• Cancer immunoediting and hijacking of the immune system
• Angiogenesis - vessels recruitment by tumor cells
• Tumor niche disruption and metastasis: the role of epithelial-mesenchymal transition (EMT)
• Case studies - Molecular Pathology perspective and impact on oncologic patients' management
• Index.