The Biology of Senescence A Translational Approach /

• Main Author: Swynghedauw, Bernard (Author, http://id.loc.gov/vocabulary/relators/aut)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Series: Practical Issues in Geriatrics,
• Subjects: Geriatrics.; General practice (Medicine).; Human genetics.; Geriatrics/Gerontology.; General Practice / Family Medicine.; Human Genetics.

This book describes the fundamental process of senescence, and reviews a new concept developed by a number of research groups that is based on cellular senescence and its secretome. This concept provides a basic explanation of the main physiological and pathological features of senescence, and delin...

Table of Contents:

• 1. Introduction
• 2. The emerging medical landscape
• 3. Origins of ageing
• 4. The senescent cell
• 5. « Benign » clinical manifestations and their relationships with the senescent cell
• 6. Age-linked non transmissible diseases
• 7. The senescent cardiovascular system
• 8. « To treat» or prevent ageing
• 9. Senescence and darwinian evolution
• 10. Conclusions
• 11. Summary
• 12. Annexes
• 13. References.