Molecular Biology of Long Non-coding RNAs

• Corporate Author: SpringerLink (Online service)
• Other Authors: Khalil, Ahmad M. (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Edition: 2nd ed. 2019.
• Subjects: Human genetics.; Proteins .; Systems biology.; Human Genetics.; Protein Science.; Systems Biology.

This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is no...

Table of Contents:

• Preface
• Chromatin regulation by long non-coding RNAs
• Regulation of Eukaryotic Cell Differentiation by Long Noncoding RNAs
• Roles of long non-coding RNAs in X-chromosome inactivation
• Roles of Long Non-Coding RNAs in Genomic Imprinting
• Dysregulation of long noncoding RNAs in human disease
• Functions of long non-coding RNAs in non-mammalian systems
• Emerging technologies to study long non-coding RNAs
• Long non coding RNAs and nuclear body formation and function
• The role of long non-coding RNAs in immunity
• Novel methods to study long non-coding RNAs
• OMICs of long non-coding RNAs
• Cancer epigenetics and long non-coding RNAs
• Roles of long non-coding RNAs in human development
• Index.