The Nociceptin/Orphanin FQ Peptide Receptor

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Ko, Mei-Chuan (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Caló, Girolamo (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Έκδοση: 1st ed. 2019.
• Σειρά: Handbook of Experimental Pharmacology, 254
• Θέματα: Pharmacology.; Neurosciences.; Anesthesiology.; Pain medicine.; Psychopharmacology.; Pharmacology/Toxicology.; Pain Medicine.

The aim of this book is not only to introduce readers with a broad spectrum of biological actions of the NOP receptor, but also to feature a detailed look at the N/OFQ-NOP receptor system, medicinal chemistry, pharmacology, and clinical data of NOP-targeted ligands. This special volume book - for th...

Πίνακας περιεχομένων:

• PART I. The N/OFQ-NOP Receptor System
• 1. The History of N/OFQ and the NOP Receptor
• 2. NOP-Targeted Peptide Ligands
• 3. NOP-Targeted Nonpeptide Ligands
• 4. Pharmacological Assays for Investigating the NOP Receptor
• 5. Electrophysiological Actions of N/OFQ
• 6. NOP Receptor Signaling Cascades
• 7.Regulation of the Genes Encoding the ppN/OFQ and NOP Receptor
• PART II. Biological Actions of NOP Ligands
• 8.NOP-Related Mechanisms in Pain and Analgesia
• 9. NOP-Related Mechanisms in Substance Use Disorders
• 10. NOP Receptor Ligands and Parkinson's Disease
• 11. NOP Ligands for the Treatment of Anxiety and Mood Disorders
• 12. The Nociceptin/Orphanin FQ System and the Regulation of Memory
• 13. N/OFQ-NOP System in Food Intake
• 14. N/OFQ-NOP System in Peripheral and Central Immunomodulation
• 15. N/OFQ-NOP System and Airways
• 16. Effects of NOP-Related Ligands in Nonhuman Primates
• PART III. First Clinical Studies with NOP Ligands
• 17. Nociceptin/Orphanin FQ and Urinary Bladder
• 18. Cebranopadol: A Novel First-in-Class Potent Analgesic Acting via NOP and Opioid Receptors
• 19. Therapeutic Approaches for NOP Receptor Antagonists in Neurobehavioral Disorders: Clinical Studies in Major Depressive Disorder and Alcohol Use Disorder with BTRX-246040 (LY2940094)
• 20. Correction to: Electrophysiological Actions of N/OFQ.