Calcitonin Gene-Related Peptide (CGRP) Mechanisms Focus on Migraine /
This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine. The various cha...
Συγγραφή απο Οργανισμό/Αρχή: | |
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Άλλοι συγγραφείς: | , |
Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
Γλώσσα: | English |
Έκδοση: |
Cham :
Springer International Publishing : Imprint: Springer,
2019.
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Έκδοση: | 1st ed. 2019. |
Σειρά: | Handbook of Experimental Pharmacology,
255 |
Θέματα: | |
Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- 1. CGRP Discovery and Timeline
- 2. CGRP Receptor Biology: Is There More Than One Receptor?
- 3. The Structure of the CGRP and Related Receptors
- 4. CGRP Receptor Signalling Pathways
- 5. Pathways of CGRP Release from Primary Sensory Neurons
- 6. CGRP in Animal Models of Migraine
- 7. CGRP in Human Models of Migraine
- 8. Role of CGRP in Migraine
- 9. Understanding CGRP and Cardiovascular Risk
- 10. CGRP and Painful Pathologies other than Headache
- 11. Calcitonin Gene-Related Peptide Antagonists and Therapeutic Antibodies.