Calcitonin Gene-Related Peptide (CGRP) Mechanisms Focus on Migraine /

This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine. The various cha...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Brain, Susan D. (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Geppetti, Pierangelo (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2019.
Έκδοση:1st ed. 2019.
Σειρά:Handbook of Experimental Pharmacology, 255
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • 1. CGRP Discovery and Timeline
  • 2. CGRP Receptor Biology: Is There More Than One Receptor?
  • 3. The Structure of the CGRP and Related Receptors
  • 4. CGRP Receptor Signalling Pathways
  • 5. Pathways of CGRP Release from Primary Sensory Neurons
  • 6. CGRP in Animal Models of Migraine
  • 7. CGRP in Human Models of Migraine
  • 8. Role of CGRP in Migraine
  • 9. Understanding CGRP and Cardiovascular Risk
  • 10. CGRP and Painful Pathologies other than Headache
  • 11. Calcitonin Gene-Related Peptide Antagonists and Therapeutic Antibodies.