The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Honn, Kenneth V. (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Zeldin, Darryl C. (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Έκδοση: 1st ed. 2019.
• Σειρά: Advances in Experimental Medicine and Biology, 1161
• Θέματα: Human genetics.; Lipids.; Human physiology.; Cell biology.; Cancer research.; Molecular biology.; Human Genetics.; Lipidology.; Human Physiology.; Cell Biology.; Cancer Research.; Molecular Medicine.

This book examines the role of bioactive lipids as pro- and anti-inflammatory mediators in the diagnosis of and as novel therapies for cardiovascular disease, cancer, ocular and neurologic diseases, and inflammatory conditions. The major pathways of arachidonic acid and omega-3 fatty acid metabolism...

Πίνακας περιεχομένων:

• Prelims
• Introduction
• Understanding the role of pro-resolving lipid mediators in infectious keratitis
• Immunoresolvent resolvin D1 maintains the health of the ocular surface
• The evolving role of specialized pro-resolving mediators in modulating neuroinflammation in perioperative neurocognitive disorders
• Relationship between specialized pro-resolving mediators and inflammatory markers in chronic cardiac disorders
• Specialized pro-resolving mediators directs cardiac healing and repair with activation of inflammation and resolution program in heart failure
• Novel n-3 docosapentaneoic acid-derived pro-resolving mediators are vasculoprotective and mediate the actions of statins in controlling inflammation
• Aspects of prostaglandin glycerol ester biology
• Targeting the COX/mPGES-1/PGE2 pathway in neuroblastoma
• Metabolomics biomarkers for precision psychiatry
• Cytochrome P450 eicosanoid signaling pathway in colorectal tumorigenesis
• Contributions of 12/15-Lipoxygenase to bleeding in the brain following ischemic stroke
• Systematic understanding of bioactive lipids in neuro-immune interactions: Lessons from an animal model of multiple sclerosis
• Role of bioactive sphingolipids in inflammation and eye diseases
• Roles of ceramides and other sphingolipids in immune cell function and inflammation
• Acute and chronic mild traumatic brain injury differentially changes levels of bioactive lipids in the CNS associated with headache
• Novel anti-inflammatory and vasodilatory ω-3 endocannabinoid epoxide regioisomers
• Overview of lipid biomarkers in Amyotrophic Lateral Sclerosis (ALS)
• Flavonoids ability to disrupt inflammation mediated by lipid and cholesterol oxidation
• Index.